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autore: Antonino Tornatore Copyright 2005 - 2025
18890
18891 Ipamorelin is a hexapeptide (six‑amino acid chain) with the
18892 sequence H‑Glu‑Thr‑Pro‑Arg‑Phe‑Lys-NH2.
18893 It was developed to act as a potent, short‑acting growth hormone
18894 releasing peptide that mimics the natural hunger
18895 hormone ghrelin. When injected subcutaneously, ipamorelin binds to GHS‑R1a receptors on somatotroph cells in the anterior pituitary gland.
18896 This binding triggers intracellular signaling cascades involving calcium influx and phospholipase C activation,
18897 ultimately leading to the secretion of growth hormone into circulation.
