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    57
    58 Oral AAS again reveal unfavorable changes, constantly growing LDL-cholesterol (38,
    59 118, 121, a hundred twenty five, 126). In the HAARLEM examine,
    60 LDL-cholesterol elevated by 0.45 mmol/L compared with baseline (46).
    61 A trial in older hypogonadal men randomized to TRT with or with out the 5α-reductase inhibitor dutasteride noted no change in CEC (137).
    62 CEC additionally remained unchanged in transgender males (female to male) present
    63 process remedy with testosterone gel or injections (138). In distinction, cross-sectional analysis demonstrated impaired CEC in AAS customers in contrast with age-matched,
    64 strength-trained nonusers and sedentary controls (139). It