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autore: Antonino Tornatore Copyright 2005 - 2025
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atleti 23790 kb in 12 files
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5117 Indeed, modifications in fat-free mass in response to graded doses of
5118 testosterone are unaffected by DHT suppression with the potent 5α-reductase inhibitor dutasteride (22).
5119
5120 The conversion of testosterone to DHT shows saturable Michaelis-Menten kinetics with an estimated
5121 in vivo Km value of three.35 nM (23). Bioactivation via
5122 this pathway right into a more potent androgen doesn't appear to happen for any of the other commonly used AAS (24).
5123 Orally ingested AAS are rapidly absorbed within the gastrointestinal
5124 (GI) tract, with serum concentrations peaking 1–2 hours after ingestion of methyltestosterone
